父亲年龄大 孩子相貌丑寿命长

 

Older fathers have uglier children, researchers have claimed after linking age to genetic¹ mutations.

 

The finding comes weeks after leading scientists reported children born to men over the age of 45 run a higher risk of having autism（孤独症） and psychiatric disorders³.

 

With age, sperm⁴-producing cells do not copy a man's DNA⁵ as effectively, leading to genetic mutations.

 

Martin Fielder, an anthropologist⁶（人类学家） at Vienna University, told the Sunday Times: 'Every 16 years the mutation² rate doubles. Other researchers found 25 mutations per sperm in a 20-year-old, but at age 40 it is 65 mutations. By 56, it doubles again.

 

'The effect is very visible - someone born to a father of 22 is already 5-10 per cent more attractive than those with a 40-year-old father and the difference grows with the age gap.'

 

In contrast, women pass on a maximum of 15 mutations to their baby, regardless of age, according to the study published in the journal Nature.

 

Surveying a group of six men and six women, researchers showed them each 4,018 photographs of 18-20-year-old men and 4,416 of women the same age, and asked to rate their attractiveness.

 

Those with older fathers were consistently rated less attractive.

 

However, the offspring of older men, though less attractive, are likely to outlive their peers with younger fathers, it is claimed.

 

Professor Lee Smith, a geneticist at Edinburgh University, told the Sunday Times other research found such children have longer telomeres（染色体终端） - the caps on the end of chromosomes⁷ - which are associated with longer life.

 

But the mounting research connecting parents' age with autism is cause for concern, experts warn.

 

Autism is an umbrella term for a range of developmental disorders that have a lifelong effect on someone's ability to interact socially and communicate.

 

In the UK, around one in 100 adults is thought to be affected⁸ by autism, mostly men, caused by a combination of genetic and environmental factors.

 

Researchers said men should be advised about the potential problems in order to help their personal decision-making when it came to having fathering children at older ages.

 

They warned that advancing paternal⁹ age posed a risk of 'numerous public health and societal problems'.

 

Among well-known older dads are Simon Cowell, 54, whose son was born earlier this month, and comedian¹⁰ Frank Skinner whose first child was born in 2012 when he was 55.

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