研究:肾移植不宜跨种族
文章来源:未知 文章作者:meng 发布时间:2009-11-02 06:28 字体: [ ]  进入论坛
(单词翻译:双击或拖选)

The race of kidney donors2 may affect the survival rates of transplant recipients4(收件人) according to a study by Henry Ford5 Hospital. "We found that transplant between races had better outcomes than transplant across races," says Anita Patel, M.D., transplant nephrologist(肾病学家) at Henry Ford Hospital Transplant Institute and lead author of the study.

"It is important to remember that the statistical6 difference in this observation is greatly outweighed7 by the life-giving benefits that recipients get from transplantation."

The study will be presented Oct. 30 at the American Society of Nephrology's Annual Meeting and Scientific Exposition in San Diego by co-investigator Rahul Pandey, M.D., a nephrology fellow.

Using data from the United Network of Organ Sharing (UNOS) of more than 158,000 recipient3 patients between 1995 and 2008, Henry Ford physicians analyzed8 the effect of donor1/recipient race disparity(不一致) on patient survival.

By regression analysis(回归分析), the non-black recipients who received a kidney from black donors had a significant lower survival rate compared to those who received a kidney from a non-black donor (hazard ratio 1.111, p=0.014) after adjusting for all known variables(变量).

"Hepatitis C(丙型肝炎) infection in the donor or recipient was seen as a significant risk factor for mortality," says Dr. Patel.

She further explains that because this is an observation from a large, national database, additional analysis of more detailed9, targeted data is needed to determine why the difference exists. Her next step involves looking at the effect of peri-transplant factors, transplant type, socioeconomic status(社会经济地位), length of dialysis(透析), immunosuppression(免疫抑制) regimes and other factors on racial disparity and mortality.

Dr. Patel presented a similar study earlier this year which looked at race and the effect on renal(肾脏的) allograft(异体移植物) survival in different donor/recipients pairs. In that study, Dr. Patel found an increased risk in graft10 failure(移植失败) in non-black recipients of non-heart beating black donor kidneys. They appeared to have a two-fold increased risk of graft failure.

According to UNOS, more than 16,000 kidney transplants were performed last year. More than 80,000 people are waiting for kidney donors, and last year, 33,000 new kidney patients joined the registry. Twelve percent of living donors are African-American.



点击收听单词发音收听单词发音  

1 donor dstxI     
n.捐献者;赠送人;(组织、器官等的)供体
参考例句:
  • In these cases,the recipient usually takes care of the donor afterwards.在这类情况下,接受捐献者以后通常会照顾捐赠者。
  • The Doctor transplanted the donor's heart to Mike's chest cavity.医生将捐赠者的心脏移植进麦克的胸腔。
2 donors 89b49c2bd44d6d6906d17dca7315044b     
n.捐赠者( donor的名词复数 );献血者;捐血者;器官捐献者
参考例句:
  • Please email us to be removed from our active list of blood donors. 假如你想把自己的名字从献血联系人名单中删去,请给我们发电子邮件。
  • About half this amount comes from individual donors and bequests. 这笔钱大约有一半来自个人捐赠及遗赠。 来自《简明英汉词典》
3 recipient QA8zF     
a.接受的,感受性强的 n.接受者,感受者,容器
参考例句:
  • Please check that you have a valid email certificate for each recipient. 请检查是否对每个接收者都有有效的电子邮件证书。
  • Colombia is the biggest U . S aid recipient in Latin America. 哥伦比亚是美国在拉丁美洲最大的援助对象。
4 recipients 972af69bf73f8ad23a446a346a6f0fff     
adj.接受的;受领的;容纳的;愿意接受的n.收件人;接受者;受领者;接受器
参考例句:
  • The recipients of the prizes had their names printed in the paper. 获奖者的姓名登在报上。 来自《简明英汉词典》
  • The recipients of prizes had their names printed in the paper. 获奖者名单登在报上。 来自《现代英汉综合大词典》
5 Ford KiIxx     
n.浅滩,水浅可涉处;v.涉水,涉过
参考例句:
  • They were guarding the bridge,so we forded the river.他们驻守在那座桥上,所以我们只能涉水过河。
  • If you decide to ford a stream,be extremely careful.如果已决定要涉过小溪,必须极度小心。
6 statistical bu3wa     
adj.统计的,统计学的
参考例句:
  • He showed the price fluctuations in a statistical table.他用统计表显示价格的波动。
  • They're making detailed statistical analysis.他们正在做具体的统计分析。
7 outweighed ab362c03a68adf0ab499937abbf51262     
v.在重量上超过( outweigh的过去式和过去分词 );在重要性或价值方面超过
参考例句:
  • This boxer outweighed by his opponent 20 pounds. 这个拳击选手体重比他的对手重20磅。 来自《简明英汉词典》
  • She outweighed me by ten pounds, and sometimes she knocked me down. 她的体重超过我十磅,有时竟把我撞倒。 来自百科语句
8 analyzed 483f1acae53789fbee273a644fdcda80     
v.分析( analyze的过去式和过去分词 );分解;解释;对…进行心理分析
参考例句:
  • The doctors analyzed the blood sample for anemia. 医生们分析了贫血的血样。 来自《简明英汉词典》
  • The young man did not analyze the process of his captivation and enrapturement, for love to him was a mystery and could not be analyzed. 这年轻人没有分析自己蛊惑著迷的过程,因为对他来说,爱是个不可分析的迷。 来自《简明英汉词典》
9 detailed xuNzms     
adj.详细的,详尽的,极注意细节的,完全的
参考例句:
  • He had made a detailed study of the terrain.他对地形作了缜密的研究。
  • A detailed list of our publications is available on request.我们的出版物有一份详细的目录备索。
10 graft XQBzg     
n.移植,嫁接,艰苦工作,贪污;v.移植,嫁接
参考例句:
  • I am having a skin graft on my arm soon.我马上就要接受手臂的皮肤移植手术。
  • The minister became rich through graft.这位部长透过贪污受贿致富。
TAG标签: patient race kidney
发表评论
请自觉遵守互联网相关的政策法规,严禁发布色情、暴力、反动的言论。
评价:
表情:
验证码:点击我更换图片