极度肥胖的青少年通过胃束带手术可有效减轻体重
文章来源:未知 文章作者:meng 发布时间:2010-02-10 00:49 字体: [ ]  进入论坛
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A higher percentage of severely1 obese2 adolescents who received laparoscopic(腹腔镜检查的) adjustable3 gastric4(胃部的) banding(捆扎) lost more than 50 percent of excess weight and experienced greater benefits to health and quality of life compared to those in an intensive lifestyle management program, according to a study in the February 10 issue of JAMA. Adolescent obesity5 is a serious health challenge globally. In the U.S., more than 17.4 percent, or more than 5 million adolescents were obese in 2004, an increase from 14.8 percent in 2000. Obesity is associated with both immediate6 and late health effects and reduced life expectancy7(平均寿命,预期寿命) , according to background information in the article. Lifestyle programs that have included changes in diet, exercise, and behavior to promote weight loss often have poor results. "Bariatric surgery is now extensively used for adults and is being evaluated for adolescents," the authors write. "Laparoscopic adjustable gastric banding (gastric banding) has the potential to provide a safe and effective treatment."

Paul E. O'Brien, M.D., F.R.A.C.S., and colleagues of Monash University and the Centre for Adolescent Health, Royal Children's Hospital, Melbourne, Australia, conducted a study to examine whether gastric banding would induce more weight loss and would provide greater health benefits and better improvement in the quality of life of severely obese adolescents than the application of currently available lifestyle approaches. The randomized(随机化的) controlled trial included 50 adolescents between 14 and 18 years of age with a body mass index (BMI身体质量指数) higher than 35 who were assigned either to participate in a supervised lifestyle intervention8 or to undergo(经历,忍受) gastric banding, and followed up for 2 years. The lifestyle intervention program included reduced calorie intake9, increased activity and behavioral modification10. The study was performed between May 2005 and September 2008. Twenty-four of 25 patients in the gastric banding group and 18 of 25 in the lifestyle group completed the study.

The researchers found that the primary outcome of greater than 50 percent of excess weight loss was achieved by 21 of 25 participants (84 percent) in the gastric banding group and 3 of 25 (12 percent) in the lifestyle group. At 2 years the gastric banding group had lost an average of about 76 lbs., representing an overall average loss of 28.3 percent of total body weight and 78.8 percent excess weight loss. The lifestyle group lost an average of 6.6 lbs., representing an average 3.1 percent total weight loss and 13.2 percent excess weight loss. The differences between groups was significant for all weight measures at 24 months.

"At entry, 9 participants (36 percent) in the gastric banding group and 10 (40 percent) in the lifestyle group had the metabolic11(新陈代谢的,变化的) syndrome12(综合症,并发症) . At 24 months, none of the gastric banding group had the metabolic syndrome compared with 4 of the 18 completers (22 percent) in the lifestyle group," the authors write. The gastric banding group experienced improved quality of life with no adverse13 events in the period shortly after surgery. However, 8 operations (33 percent) involving revisional(修正的) procedures were required in 7 patients in the surgery group.

"In this study, gastric banding proved to be an effective intervention leading to a substantial(大量的,实质的) and durable14(耐用的,持久的) reduction in obesity and to better health. The adolescent and parents must understand the importance of careful adherence15 to(遵守) recommended eating behaviors and of seeking early consultation16 if symptoms of reflux(逆流,退潮) , heartburn(心痛,胃灼热) , or vomiting17 occur. As importantly, they should be in a setting in which they can maintain contact with health professionals who understand the process of care. This study indicates that, in such a setting, the laparoscopic adjustable gastric banding process can achieve important improvements in weight, health, and quality of life in severely obese adolescents," the researchers conclude.



点击收听单词发音收听单词发音  

1 severely SiCzmk     
adv.严格地;严厉地;非常恶劣地
参考例句:
  • He was severely criticized and removed from his post.他受到了严厉的批评并且被撤了职。
  • He is severely put down for his careless work.他因工作上的粗心大意而受到了严厉的批评。
2 obese uvIya     
adj.过度肥胖的,肥大的
参考例句:
  • The old man is really obese,it can't be healthy.那位老人确实过于肥胖了,不能算是健康。
  • Being obese and lazy is dangerous to health.又胖又懒危害健康。
3 adjustable vzOzkc     
adj.可调整的,可校准的
参考例句:
  • More expensive cameras have adjustable focusing.比较贵的照相机有可调焦距。
  • The chair has the virtue of being adjustable.这种椅子具有可调节的优点。
4 gastric MhnxW     
adj.胃的
参考例句:
  • Miners are a high risk group for certain types of gastric cancer.矿工是极易患某几种胃癌的高风险人群。
  • That was how I got my gastric trouble.我的胃病就是这么得的。
5 obesity Dv1ya     
n.肥胖,肥大
参考例句:
  • One effect of overeating may be obesity.吃得过多能导致肥胖。
  • Sugar and fat can more easily lead to obesity than some other foods.糖和脂肪比其他食物更容易导致肥胖。
6 immediate aapxh     
adj.立即的;直接的,最接近的;紧靠的
参考例句:
  • His immediate neighbours felt it their duty to call.他的近邻认为他们有责任去拜访。
  • We declared ourselves for the immediate convocation of the meeting.我们主张立即召开这个会议。
7 expectancy tlMys     
n.期望,预期,(根据概率统计求得)预期数额
参考例句:
  • Japanese people have a very high life expectancy.日本人的平均寿命非常长。
  • The atomosphere of tense expectancy sobered everyone.这种期望的紧张气氛使每个人变得严肃起来。
8 intervention e5sxZ     
n.介入,干涉,干预
参考例句:
  • The government's intervention in this dispute will not help.政府对这场争论的干预不会起作用。
  • Many people felt he would be hostile to the idea of foreign intervention.许多人觉得他会反对外来干预。
9 intake 44cyQ     
n.吸入,纳入;进气口,入口
参考例句:
  • Reduce your salt intake.减少盐的摄入量。
  • There was a horrified intake of breath from every child.所有的孩子都害怕地倒抽了一口凉气。
10 modification tEZxm     
n.修改,改进,缓和,减轻
参考例句:
  • The law,in its present form,is unjust;it needs modification.现行的法律是不公正的,它需要修改。
  • The design requires considerable modification.这个设计需要作大的修改。
11 metabolic 2R4z1     
adj.新陈代谢的
参考例句:
  • Impressive metabolic alternations have been undergone during embryogenesis.在胚胎发生期间经历了深刻的代谢变化。
  • A number of intoxicants are associated with metabolic acidosis.许多毒性物质可引起代谢性酸中毒。
12 syndrome uqBwu     
n.综合病症;并存特性
参考例句:
  • The Institute says that an unidentified virus is to blame for the syndrome. 该研究所表示,引起这种综合症的是一种尚未确认的病毒。
  • Results indicated that 11 fetuses had Down syndrome. 结果表明有11个胎儿患有唐氏综合征。
13 adverse 5xBzs     
adj.不利的;有害的;敌对的,不友好的
参考例句:
  • He is adverse to going abroad.他反对出国。
  • The improper use of medicine could lead to severe adverse reactions.用药不当会产生严重的不良反应。
14 durable frox4     
adj.持久的,耐久的
参考例句:
  • This raincoat is made of very durable material.这件雨衣是用非常耐用的料子做的。
  • They frequently require more major durable purchases.他们经常需要购买耐用消费品。
15 adherence KyjzT     
n.信奉,依附,坚持,固着
参考例句:
  • He was well known for his adherence to the rules.他因遵循这些规定而出名。
  • The teacher demanded adherence to the rules.老师要求学生们遵守纪律。
16 consultation VZAyq     
n.咨询;商量;商议;会议
参考例句:
  • The company has promised wide consultation on its expansion plans.该公司允诺就其扩展计划广泛征求意见。
  • The scheme was developed in close consultation with the local community.该计划是在同当地社区密切磋商中逐渐形成的。
17 vomiting 7ed7266d85c55ba00ffa41473cf6744f     
参考例句:
  • Symptoms include diarrhoea and vomiting. 症状有腹泻和呕吐。
  • Especially when I feel seasick, I can't stand watching someone else vomiting." 尤其晕船的时候,看不得人家呕。”
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