正常体重的糖尿病患者死亡率更高
文章来源:未知 文章作者:enread 发布时间:2012-08-08 05:07 字体: [ ]  进入论坛
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American adults of a normal weight with new-onset diabetes1 die at a higher rate than overweight/obese2 adults with the same disease, according to a new Northwestern Medicine study. The study, to be published in the Aug. 7 issue of JAMA, found that normal-weight participants experienced both significantly higher total and non-cardiovascular(心血管的) mortality than overweight/obese participants.
 
Normal-weight adults with type 2 diabetes have been understudied because those who typically develop the disease are overweight or obese. In this study about 10 percent of those with new-onset diabetes were at a normal weight at the time of ascertainment(确定,发现).
 
Being overweight is a risk factor for developing this disease, but other risk factors such as family history, ethnicity and age may play a role.
 
"It could be that this is a very unique subset of the population who are at a particularly high risk for mortality and diabetes, and it is possible that genetics is a factor with these individuals," said Mercedes R. Carnethon, associate professor of preventive medicine at Northwestern University Feinberg School of Medicine and first author of the study.
 
Older adults and nonwhite participants are more likely to experience normal-weight diabetes, according to the study.
 
"Many times physicians don't expect that normal-weight people have diabetes when it is quite possible that they do and could be at a high risk of mortality, particularly if they are older adults or members of a minority group," Carnethon said. "If you are of a normal weight and have new-onset diabetes, talk to your doctor about controlling your health risks, including cardiovascular risk factors."
 
Researchers analyzed4 data from five cohort studies and identified 2,625 U.S. men and women over the age of 40 who were determined5 to have diabetes at the start of the studies. Some of these individuals already knew they were diabetic, and others found out through their participation6 in the studies.
 
Diabetes determination was based on a fasting glucose7 of 126 mg/dL or greater or newly initiated8 diabetes medication with concurrent9 measurements of body mass index (BMI). A participant of normal weight had a BMI of 18.5 to 24.99, while overweight/obese participants had a BMI of 25 or greater.
 
With the aging and diversification10 of the population, cases of normal weight diabetes likely will be on the rise, Carnethon said. Future studies should focus on factors such as fat distribution and genetic3 types in normal-weight people with diabetes, she said.


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1 diabetes uPnzu     
n.糖尿病
参考例句:
  • In case of diabetes, physicians advise against the use of sugar.对于糖尿病患者,医生告诫他们不要吃糖。
  • Diabetes is caused by a fault in the insulin production of the body.糖尿病是由体內胰岛素分泌失调引起的。
2 obese uvIya     
adj.过度肥胖的,肥大的
参考例句:
  • The old man is really obese,it can't be healthy.那位老人确实过于肥胖了,不能算是健康。
  • Being obese and lazy is dangerous to health.又胖又懒危害健康。
3 genetic PgIxp     
adj.遗传的,遗传学的
参考例句:
  • It's very difficult to treat genetic diseases.遗传性疾病治疗起来很困难。
  • Each daughter cell can receive a full complement of the genetic information.每个子细胞可以收到遗传信息的一个完全补偿物。
4 analyzed 483f1acae53789fbee273a644fdcda80     
v.分析( analyze的过去式和过去分词 );分解;解释;对…进行心理分析
参考例句:
  • The doctors analyzed the blood sample for anemia. 医生们分析了贫血的血样。 来自《简明英汉词典》
  • The young man did not analyze the process of his captivation and enrapturement, for love to him was a mystery and could not be analyzed. 这年轻人没有分析自己蛊惑著迷的过程,因为对他来说,爱是个不可分析的迷。 来自《简明英汉词典》
5 determined duszmP     
adj.坚定的;有决心的
参考例句:
  • I have determined on going to Tibet after graduation.我已决定毕业后去西藏。
  • He determined to view the rooms behind the office.他决定查看一下办公室后面的房间。
6 participation KS9zu     
n.参与,参加,分享
参考例句:
  • Some of the magic tricks called for audience participation.有些魔术要求有观众的参与。
  • The scheme aims to encourage increased participation in sporting activities.这个方案旨在鼓励大众更多地参与体育活动。
7 glucose Fyiyz     
n.葡萄糖
参考例句:
  • I gave him an extra dose of glucose to pep him up.我给他多注射了一剂葡萄糖以增强他的活力。
  • The doctor injected glucose into his patient's veins.医生将葡萄糖注入病人的静脉。
8 initiated 9cd5622f36ab9090359c3cf3ca4ddda3     
n. 创始人 adj. 新加入的 vt. 开始,创始,启蒙,介绍加入
参考例句:
  • He has not yet been thoroughly initiated into the mysteries of computers. 他对计算机的奥秘尚未入门。
  • The artist initiated the girl into the art world in France. 这个艺术家介绍这个女孩加入巴黎艺术界。
9 concurrent YncyG     
adj.同时发生的,一致的
参考例句:
  • You can't attend two concurrent events!你不能同时参加两项活动!
  • The twins had concurrent birthday. 双胞胎生日在同一天。
10 diversification 8scxf     
n.变化,多样化;多种经营
参考例句:
  • The seminar was to discuss diversification of agriculture. 该研讨会讨论的是农业多种经营。 来自辞典例句
  • Firm diversification is increasingly achieved by the means of takeover and merger. 通过接管和兼并,厂商经营范围日益多样化。 来自辞典例句
TAG标签: weight disease diabetes
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