结肠癌患者不宜多吃淀粉类、高碳水化合物食物
文章来源:未知 文章作者:enread 发布时间:2012-11-08 05:37 字体: [ ]  进入论坛
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Colon1 cancer survivors2 whose diet is heavy in complex sugars and carbohydrate3-rich foods are far more likely to have a recurrence5 of the disease than are patients who eat a better balance of foods, a new study by Dana-Farber Cancer Institute researchers indicates. The connection is especially strong in patients who are overweight or obese6, the authors write. More than 1,000 patients with advanced (stage III) colon cancer participated in the study, one of the first to examine how diet can affect the chances that the disease will recur4.
 
The findings are being published online by the Journal of the National Cancer Institute and will appear later in the journal's print edition.
 
Although the results point to a potential hazard, for colon cancer patients, of a high-carbohydrate diet, the take-home message is not a conclusive7 "Eat less sugar," said lead author Jeffrey Meyerhardt, MD, MPH. "Our study certainly supports the idea that diet can impact the progression of colon cancer, and that patients and their doctors should consider this when making post-treatment plans. But further research is needed to confirm our findings."
 
Recent studies have shown that colorectal cancer survivors whose diet and activity patterns lead to excess amounts of insulin in the blood have a higher risk of cancer recurrence and death from the disease. High insulin levels can be produced by eating too many starchy and sugar-laden foods. In a previous study of advanced-stage colon cancer patients, Meyerhardt and his colleagues found that those with a typical "Western" diet -- marked by high intakes9 of meat, fat, refined grains, and sugar desserts -- were three times more likely to have a cancer recurrence than those whose diets were least Western. The new study was conducted to explore which component10 of the Western diet is most responsible for the increased risk of recurrence.
 
The study involved 1,011 stage III colon cancer patients who had undergone surgery and participated in a National Cancer Institute-sponsored Cancer and Leukemia Group B clinical trial of follow-up chemotherapy for their disease. Participants reported their dietary intake8 during and six months after the trial.
 
Researchers tracked the patients' total carbohydrates11, as well as their glycemic(血糖的) index (a measure of how quickly blood sugar levels rise after eating a particular food), and glycemic load (which takes into account the amount of a carbohydrate actually consumed), and looked for a statistical12 connection between these measures and the recurrence of colon cancer.
 
They found that participants with the highest dietary levels of glycemic load and carbohydrate intake had an 80 percent increased risk of colon cancer recurrence or death compared with those who had the lowest levels. Among patients who were overweight or obese (had a body mass index above 25 kg/m2), the increase was even greater.
 
"In light of our and other's research, we theorize that factors including a high glycemic load may stimulate13 the body's production of insulin," Meyerhardt said. "That, in turn, may increase the proliferation of cells and prevent the natural cell-death process in cancer cells that have metastasized from their original site."
 
Meyerhardt added that while the study doesn't prove that diets high in glycemic load and carbohydrate intake cause recurrence of colon cancer, the results strongly suggest that such dietary factors play a role. "Our findings may offer useful guidance for patients and physicians in ways of improving patient survival after treatment."


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1 colon jqfzJ     
n.冒号,结肠,直肠
参考例句:
  • Here,too,the colon must be followed by a dash.这里也是一样,应当在冒号后加破折号。
  • The colon is the locus of a large concentration of bacteria.结肠是大浓度的细菌所在地。
2 survivors 02ddbdca4c6dba0b46d9d823ed2b4b62     
幸存者,残存者,生还者( survivor的名词复数 )
参考例句:
  • The survivors were adrift in a lifeboat for six days. 幸存者在救生艇上漂流了六天。
  • survivors clinging to a raft 紧紧抓住救生筏的幸存者
3 carbohydrate FTPy0     
n.碳水化合物;糖类;(plural)淀粉质或糖类
参考例句:
  • You should not have too much carbohydrate in your diet.你日常饮食中不该有过多碳水化合物。
  • Cashew nuts are rich in carbohydrate.腰果含丰富碳水化合物。
4 recur wCqyG     
vi.复发,重现,再发生
参考例句:
  • Economic crises recur periodically.经济危机周期性地发生。
  • Of course,many problems recur at various periods.当然,有许多问题会在不同的时期反复提出。
5 recurrence ckazKP     
n.复发,反复,重现
参考例句:
  • More care in the future will prevent recurrence of the mistake.将来的小心可防止错误的重现。
  • He was aware of the possibility of a recurrence of his illness.他知道他的病有可能复发。
6 obese uvIya     
adj.过度肥胖的,肥大的
参考例句:
  • The old man is really obese,it can't be healthy.那位老人确实过于肥胖了,不能算是健康。
  • Being obese and lazy is dangerous to health.又胖又懒危害健康。
7 conclusive TYjyw     
adj.最后的,结论的;确凿的,消除怀疑的
参考例句:
  • They produced some fairly conclusive evidence.他们提供了一些相当确凿的证据。
  • Franklin did not believe that the French tests were conclusive.富兰克林不相信这个法国人的实验是结论性的。
8 intake 44cyQ     
n.吸入,纳入;进气口,入口
参考例句:
  • Reduce your salt intake.减少盐的摄入量。
  • There was a horrified intake of breath from every child.所有的孩子都害怕地倒抽了一口凉气。
9 intakes 8ef0c0b97d557507433c00f72a6fc6e2     
吸入( intake的名词复数 ); (液体等)进入口; (一定时期内)进入或纳入的人数; (采煤)进风巷道
参考例句:
  • The Tornado jet fighter-bomber has two air intakes. 旋风式喷气轰炸机有两个空气入口。
  • The air intakes to the carburetors were filling up with freezing snow. 汽化器的进气道被积雪封住了。 来自英汉非文学 - 百科语料821
10 component epSzv     
n.组成部分,成分,元件;adj.组成的,合成的
参考例句:
  • Each component is carefully checked before assembly.每个零件在装配前都经过仔细检查。
  • Blade and handle are the component parts of a knife.刀身和刀柄是一把刀的组成部分。
11 carbohydrates 001f0186d1ea717492c413ca718f2635     
n.碳水化合物,糖类( carbohydrate的名词复数 );淀粉质或糖类食物
参考例句:
  • The plant uses the carbohydrates to make cellulose. 植物用碳水化合物制造纤维素。 来自《简明英汉词典》
  • All carbohydrates originate from plants. 所有的碳水化合物均来自植物。 来自辞典例句
12 statistical bu3wa     
adj.统计的,统计学的
参考例句:
  • He showed the price fluctuations in a statistical table.他用统计表显示价格的波动。
  • They're making detailed statistical analysis.他们正在做具体的统计分析。
13 stimulate wuSwL     
vt.刺激,使兴奋;激励,使…振奋
参考例句:
  • Your encouragement will stimulate me to further efforts.你的鼓励会激发我进一步努力。
  • Success will stimulate the people for fresh efforts.成功能鼓舞人们去作新的努力。
TAG标签: foods cancer colon
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