A team of scientists from around the world led by Baylor College of Medicine and Washington University in St. Louis has completed the genome sequence of the common marmoset（狨猴） -- the first sequence of a New World Monkey -- providing new information about the marmoset's unique rapid reproductive system, physiology¹ and growth, shedding new light on primate² biology and evolution. The team published the work today in the journal Nature Genetics.

 

"We study primate genomes to get a better understanding of the biology of the species that are most closely related to humans," said Dr. Jeffrey Rogers, associate professor in the Human Genome Sequencing Center at Baylor and a lead author on the report. "The previous sequences of the great apes and macaques（猕猴）, which are very closely related to humans on the primate evolutionary³ tree, have provided remarkable⁴ new information about the evolutionary origins of the human genome and the processes involved."

 

With the sequence of the marmoset, the team revealed for the first time the genome of a non-human primate in the New World monkeys, which represents a separate branch in the primate evolutionary tree that is more distant from humans than those whose genomes have been studied in detail before. The sequence allows researchers to broaden their ability to study the human genome and its history as revealed by comparison with other primates⁵.

 

The sequencing was conducted jointly⁶ by Baylor and Washington University and led by Dr. Kim Worley, professor in the Human Genome Sequencing Center, and Rogers at Baylor, and Drs. Richard K. Wilson, director, and Wesley Warren of The Genome Institute at Washington University, in collaboration⁷ with Dr. Suzette Tardif of The University of Texas Health Science Center in San Antonio and the Southwest National Primate Research Center.

 

"Each new non-human primate genome adds to a deeper understanding of human biology," said Dr. Richard Gibbs, director of the Human Genome Sequencing Center at Baylor and a principal investigator⁸ of the study.

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