down and out 　失业，不走运

 
例句：

The bum¹ was down and out on skid² row.  这个流浪汉是贫民区的一个失业者。

The writer was down and out, but he still went on with his writing.  那个作家虽然已经穷困潦倒了，但他还是继续写作。