肥胖与吸烟会降低类风湿早期的疗效
文章来源:未知 文章作者:enread 发布时间:2016-06-10 07:37 字体: [ ]  进入论坛
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London, United Kingdom, June 9, 2016: The results of a study presented today at the European League Against Rheumatism1 Annual Congress (EULAR 2016) showed that the likelihood of achieving sustained remission in early rheumatoid arthritis2 (RA) is significantly lower in patients who smoke and who are obese3. These findings suggest that encouraging patients to stop smoking and to achieve a healthy body weight could significantly improve their chance of becoming symptom-free after adequate treatment. EULAR recommendations state that remission (absent disease activity) is the target of treatment in patients with RA. However, many patients fail to achieve or maintain remission; within ten years of onset4, at least 50% of patients in developed countries are unable to maintain a full-time5 job. 
 
"Despite the high prevalence of excess body weight and smoking among RA patients, relatively6 little is known about whether and to what extent these modifiable lifestyle factors impact the likelihood of achieving sustained remission," said study investigator7 Dr Susan Bartlett from McGill University in Montreal, Canada. "Our findings show that not smoking and a healthy body weight - lifestyle factors which can be modified by patients - can have a significant impact on becoming symptom-free." 
 
Rheumatoid Arthritis is a chronic8 disabling disease that affects the joints9, connective tissues, muscle, tendons, and fibrous tissue, causing pain and deformity. The prevalence of RA globally varies between 0.3% and 1% and is more common in women and in developed countries.3 
 
The independent effects of Body Mass Index class (normal weight: 18.5-24.9, overweight: 25-29.9, obese: 30+) and smoking on time to sustained remission in the first three years shortly after diagnosis10 were estimated in patients with early rheumatoid arthritis who had been enrolled11 into the large real world Canadian Early Arthritis Cohort (CATCH) study.


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1 rheumatism hDnyl     
n.风湿病
参考例句:
  • The damp weather plays the very devil with my rheumatism.潮湿的天气加重了我的风湿病。
  • The hot weather gave the old man a truce from rheumatism.热天使这位老人暂时免受风湿病之苦。
2 arthritis XeyyE     
n.关节炎
参考例句:
  • Rheumatoid arthritis has also been linked with the virus.风湿性关节炎也与这种病毒有关。
  • He spent three months in the hospital with acute rheumatic arthritis.他患急性风湿性关节炎,在医院住了三个月。
3 obese uvIya     
adj.过度肥胖的,肥大的
参考例句:
  • The old man is really obese,it can't be healthy.那位老人确实过于肥胖了,不能算是健康。
  • Being obese and lazy is dangerous to health.又胖又懒危害健康。
4 onset bICxF     
n.进攻,袭击,开始,突然开始
参考例句:
  • The drug must be taken from the onset of the infection.这种药必须在感染的最初期就开始服用。
  • Our troops withstood the onset of the enemy.我们的部队抵挡住了敌人的进攻。
5 full-time SsBz42     
adj.满工作日的或工作周的,全时间的
参考例句:
  • A full-time job may be too much for her.全天工作她恐怕吃不消。
  • I don't know how she copes with looking after her family and doing a full-time job.既要照顾家庭又要全天工作,我不知道她是如何对付的。
6 relatively bkqzS3     
adv.比较...地,相对地
参考例句:
  • The rabbit is a relatively recent introduction in Australia.兔子是相对较新引入澳大利亚的物种。
  • The operation was relatively painless.手术相对来说不痛。
7 investigator zRQzo     
n.研究者,调查者,审查者
参考例句:
  • He was a special investigator for the FBI.他是联邦调查局的特别调查员。
  • The investigator was able to deduce the crime and find the criminal.调查者能够推出犯罪过程并锁定罪犯。
8 chronic BO9zl     
adj.(疾病)长期未愈的,慢性的;极坏的
参考例句:
  • Famine differs from chronic malnutrition.饥荒不同于慢性营养不良。
  • Chronic poisoning may lead to death from inanition.慢性中毒也可能由虚弱导致死亡。
9 joints d97dcffd67eca7255ca514e4084b746e     
接头( joint的名词复数 ); 关节; 公共场所(尤指价格低廉的饮食和娱乐场所) (非正式); 一块烤肉 (英式英语)
参考例句:
  • Expansion joints of various kinds are fitted on gas mains. 各种各样的伸缩接头被安装在煤气的总管道上了。
  • Expansion joints of various kinds are fitted on steam pipes. 各种各样的伸缩接头被安装在蒸气管道上了。
10 diagnosis GvPxC     
n.诊断,诊断结果,调查分析,判断
参考例句:
  • His symptoms gave no obvious pointer to a possible diagnosis.他的症状无法作出明确的诊断。
  • The engineer made a complete diagnosis of the bridge's collapse.工程师对桥的倒塌做一次彻底的调查分析。
11 enrolled ff7af27948b380bff5d583359796d3c8     
adj.入学登记了的v.[亦作enrol]( enroll的过去式和过去分词 );登记,招收,使入伍(或入会、入学等),参加,成为成员;记入名册;卷起,包起
参考例句:
  • They have been studying hard from the moment they enrolled. 从入学时起,他们就一直努力学习。 来自《简明英汉词典》
  • He enrolled with an employment agency for a teaching position. 他在职业介绍所登了记以谋求一个教师的职位。 来自《简明英汉词典》
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