他汀类药物能减少中风病人的感染几率
文章来源:未知 文章作者:enread 发布时间:2016-06-19 08:46 字体: [ ]  进入论坛
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A Washington State University researcher has found that statin drugs can dramatically lower the risk of infections in stroke patients. Doug Weeks, an adjunct professor in the Elson S. Floyd College of Medicine and director of research at St. Luke's Rehabilitation1 Institute, analyzed2 the records of more than 1,600 hospitalized patients who suffered an ischemic stroke and found statins reduced the risk of infection by 58 percent. Ischemic strokes are due to blockage3 of a vessel4 that supplies blood to the brain. His findings appear online this month in the Journal of Stroke and Cerebrovascular Diseases.
 
"If patients had statins before there was evidence of an infection, there was a reduced risk that they would actually develop an infection," said Weeks.
 
Statins are typically used to lower cholesterol5 levels to reduce the risk of cardiovascular disease. But in the past decade, said Weeks, researchers have noticed that they also have anti-inflammatory properties in humans that can benefit the body's response to infection.
 
Weeks analyzed data of hospitalized stroke patients and saw that those on statins upon admission or early in their stay had significantly lower risk for developing infections than those put on statins later in their hospitalization or not at all. Weeks controlled for other possible influences like the severity of strokes, age and the presence of other conditions like diabetes6.
 
He and his colleagues also noticed that the timing7 of the drug was a major factor.
 
"The administration of statins relative to infection is critically important," he said. "We've been able to establish that if statins are given early, before infection can occur, the risk of infection is substantially reduced. However, this relationship needs to be tested in more rigorous placebo-controlled studies to see if this benefit with statins is maintained."


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1 rehabilitation 8Vcxv     
n.康复,悔过自新,修复,复兴,复职,复位
参考例句:
  • He's booked himself into a rehabilitation clinic.他自己联系了一家康复诊所。
  • No one can really make me rehabilitation of injuries.已经没有人可以真正令我的伤康复了。
2 analyzed 483f1acae53789fbee273a644fdcda80     
v.分析( analyze的过去式和过去分词 );分解;解释;对…进行心理分析
参考例句:
  • The doctors analyzed the blood sample for anemia. 医生们分析了贫血的血样。 来自《简明英汉词典》
  • The young man did not analyze the process of his captivation and enrapturement, for love to him was a mystery and could not be analyzed. 这年轻人没有分析自己蛊惑著迷的过程,因为对他来说,爱是个不可分析的迷。 来自《简明英汉词典》
3 blockage XRxyc     
n.障碍物;封锁
参考例句:
  • The logical treatment is to remove this blockage.合理的治疗方法就是清除堵塞物。
  • If the blockage worked,they could retreat with dignity.如果封锁发生作用,他们可以体面地撤退。
4 vessel 4L1zi     
n.船舶;容器,器皿;管,导管,血管
参考例句:
  • The vessel is fully loaded with cargo for Shanghai.这艘船满载货物驶往上海。
  • You should put the water into a vessel.你应该把水装入容器中。
5 cholesterol qrzzV     
n.(U)胆固醇
参考例句:
  • There is cholesterol in the cell of body.人体细胞里有胆固醇。
  • They are determining the serum-protein and cholesterol levels.他们正在测定血清蛋白和胆固醇的浓度。
6 diabetes uPnzu     
n.糖尿病
参考例句:
  • In case of diabetes, physicians advise against the use of sugar.对于糖尿病患者,医生告诫他们不要吃糖。
  • Diabetes is caused by a fault in the insulin production of the body.糖尿病是由体內胰岛素分泌失调引起的。
7 timing rgUzGC     
n.时间安排,时间选择
参考例句:
  • The timing of the meeting is not convenient.会议的时间安排不合适。
  • The timing of our statement is very opportune.我们发表声明选择的时机很恰当。
TAG标签: drugs stroke statin
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