星形高分子可杀灭超级细菌
文章来源:未知 文章作者:enread 发布时间:2016-12-19 02:18 字体: [ ]  进入论坛
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The study, published today in Nature Microbiology, holds promise for a new treatment method against antibiotic1-resistant bacteria (commonly known as superbugs). The star-shaped structures, are short chains of proteins called 'peptide polymers', and were created by a team from the Melbourne School of Engineering.
 
The team included Professor Greg Qiao and PhD candidate Shu Lam, from the Department of Chemical and Biomolecular Engineering, as well as Associate Professor Neil O'Brien-Simpson and Professor Eric Reynolds from the Faculty2 of Medicine, Dentistry and Health Sciences and Bio21 Institute.
 
Professor Qiao said that currently the only treatment for infections caused by bacteria is antibiotics3. However, over time bacteria mutate to protect themselves against antibiotics, making treatment no longer effective. These mutated bacteria are known as 'superbugs'.
 
"It is estimated that the rise of superbugs will cause up to ten million deaths a year by 2050. In addition, there have only been one or two new antibiotics developed in the last 30 years," he said.
 
Professor Qiao and his team have been working with peptide polymers in the past few years. Recently, the team created a star-shaped peptide polymer that was extremely effective at killing4 Gram-negative bacteria - a major class of bacteria known to be highly prone5 to antibiotic resistance - while being non-toxic6 to the body. 
 
In fact, tests undertaken on red blood cells showed that the star-shaped polymer dosage rate would need to be increased by a factor of greater than 100 to become toxic.
 
The star-shaped peptide polymer is also effective in killing superbugs when tested in animal models. Furthermore, superbugs showed no signs of resistance against these peptide polymers.


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1 antibiotic KNJzd     
adj.抗菌的;n.抗生素
参考例句:
  • The doctor said that I should take some antibiotic.医生说我应该服些用抗生素。
  • Antibiotic can be used against infection.抗菌素可以用来防止感染。
2 faculty HhkzK     
n.才能;学院,系;(学院或系的)全体教学人员
参考例句:
  • He has a great faculty for learning foreign languages.他有学习外语的天赋。
  • He has the faculty of saying the right thing at the right time.他有在恰当的时候说恰当的话的才智。
3 antibiotics LzgzQT     
n.(用作复数)抗生素;(用作单数)抗生物质的研究;抗生素,抗菌素( antibiotic的名词复数 )
参考例句:
  • the discovery of antibiotics in the 20th century 20世纪抗生素的发现
  • The doctor gave me a prescription for antibiotics. 医生给我开了抗生素。
4 killing kpBziQ     
n.巨额利润;突然赚大钱,发大财
参考例句:
  • Investors are set to make a killing from the sell-off.投资者准备清仓以便大赚一笔。
  • Last week my brother made a killing on Wall Street.上个周我兄弟在华尔街赚了一大笔。
5 prone 50bzu     
adj.(to)易于…的,很可能…的;俯卧的
参考例句:
  • Some people are prone to jump to hasty conclusions.有些人往往作出轻率的结论。
  • He is prone to lose his temper when people disagree with him.人家一不同意他的意见,他就发脾气。
6 toxic inSwc     
adj.有毒的,因中毒引起的
参考例句:
  • The factory had accidentally released a quantity of toxic waste into the sea.这家工厂意外泄漏大量有毒废物到海中。
  • There is a risk that toxic chemicals might be blasted into the atmosphere.爆炸后有毒化学物质可能会进入大气层。
TAG标签: bacteria proteins polymers
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