老年痴呆症对女性的影响大于男性
文章来源:未知 文章作者:enread 发布时间:2017-01-08 08:17 字体: [ ]  进入论坛
(单词翻译:双击或拖选)
For more than 25 years, Mary Read was a successful nurse in Lititz, Pennsylvania. But in 2010, at the age of 50, she started having trouble with her memory and thinking, making it difficult for her to complete routine tasks and follow instructions at work. The problems worsened, bringing her career to an abrupt1 end. In 2011, her doctor conducted a comprehensive evaluation2, including a cognitive3 assessment4, and found that she was in the early stages of younger-onset Alzheimer's, which affects hundreds of thousands of people under 65.
 
A year earlier, Elizabeth Wolf faced another sort of upheaval5. The 36-year-old community health program director was forced to abandon her own career, home and community in Vermont when both of her parents were diagnosed with Alzheimer's three months apart. Wolf took the difficult decision to move back into her childhood home in Mount Laurel, New Jersey6 in order to become their primary caregiver.
 
These stories are not unusual. Alzheimer's dementia disproportionately affects women in a variety of ways. Compared with men, 2.5 times as many women as men provide 24-hour care for an affected7 relative. Nearly 19 percent of these wives, sisters and daughters have had to quit work to do so. In addition, women make up nearly two-thirds of the more than 5 million Americans living with Alzheimer's today. According to the Alzheimer's Association 2016 Alzheimer's Disease Facts and Figures, an estimated 3.3 million women aged8 65 and older in the United States have the disease. To put that number in perspective, a woman in her sixties is now about twice as likely to develop Alzheimer's as breast cancer within her lifetime.
 
Researchers are racing9 to figure out why. Women generally live longer than men, but mounting evidence suggests that longevity10 alone may not account for the unequal disease burden women face. It remains11 unclear whether women are truly at an increased risk for Alzheimer's. But studies have revealed that there may be distinct biological and genetic12 factors shaping how the disease develops and progresses in women. Understanding these differences will be of key importance in devising new, more effective strategies for treating, preventing and diagnosing Alzheimer's.
 
Consider the example of heart disease. The death rate dropped by nearly half as awareness13 that it was the leading cause of death in women rose dramatically during a 12-year period beginning in 1997. Now, research uncovering biological differences in heart disease is continuing to help doctors fine-tune diagnosis14, prevention and treatment for women. For example, cardiologists are modifying how they identify potential risk factors, adjusting blood thinner dosages, and prescribing low-dose aspirin15 depending on a person's sex, particularly for older women who have already had a heart attack. Tackling Alzheimer's now requires a similar vision.


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1 abrupt 2fdyh     
adj.突然的,意外的;唐突的,鲁莽的
参考例句:
  • The river takes an abrupt bend to the west.这河突然向西转弯。
  • His abrupt reply hurt our feelings.他粗鲁的回答伤了我们的感情。
2 evaluation onFxd     
n.估价,评价;赋值
参考例句:
  • I attempted an honest evaluation of my own life.我试图如实地评价我自己的一生。
  • The new scheme is still under evaluation.新方案还在评估阶段。
3 cognitive Uqwz0     
adj.认知的,认识的,有感知的
参考例句:
  • As children grow older,their cognitive processes become sharper.孩子们越长越大,他们的认知过程变得更为敏锐。
  • The cognitive psychologist is like the tinker who wants to know how a clock works.认知心理学者倒很像一个需要通晓钟表如何运转的钟表修理匠。
4 assessment vO7yu     
n.评价;评估;对财产的估价,被估定的金额
参考例句:
  • This is a very perceptive assessment of the situation.这是一个对该情况的极富洞察力的评价。
  • What is your assessment of the situation?你对时局的看法如何?
5 upheaval Tp6y1     
n.胀起,(地壳)的隆起;剧变,动乱
参考例句:
  • It was faced with the greatest social upheaval since World War Ⅱ.它面临第二次世界大战以来最大的社会动乱。
  • The country has been thrown into an upheaval.这个国家已经陷入动乱之中。
6 jersey Lp5zzo     
n.运动衫
参考例句:
  • He wears a cotton jersey when he plays football.他穿运动衫踢足球。
  • They were dressed alike in blue jersey and knickers.他们穿着一致,都是蓝色的运动衫和灯笼短裤。
7 affected TzUzg0     
adj.不自然的,假装的
参考例句:
  • She showed an affected interest in our subject.她假装对我们的课题感到兴趣。
  • His manners are affected.他的态度不自然。
8 aged 6zWzdI     
adj.年老的,陈年的
参考例句:
  • He had put on weight and aged a little.他胖了,也老点了。
  • He is aged,but his memory is still good.他已年老,然而记忆力还好。
9 racing 1ksz3w     
n.竞赛,赛马;adj.竞赛用的,赛马用的
参考例句:
  • I was watching the racing on television last night.昨晚我在电视上看赛马。
  • The two racing drivers fenced for a chance to gain the lead.两个赛车手伺机竞相领先。
10 longevity C06xQ     
n.长命;长寿
参考例句:
  • Good habits promote longevity.良好的习惯能增长寿命。
  • Human longevity runs in families.人类的长寿具有家族遗传性。
11 remains 1kMzTy     
n.剩余物,残留物;遗体,遗迹
参考例句:
  • He ate the remains of food hungrily.他狼吞虎咽地吃剩余的食物。
  • The remains of the meal were fed to the dog.残羹剩饭喂狗了。
12 genetic PgIxp     
adj.遗传的,遗传学的
参考例句:
  • It's very difficult to treat genetic diseases.遗传性疾病治疗起来很困难。
  • Each daughter cell can receive a full complement of the genetic information.每个子细胞可以收到遗传信息的一个完全补偿物。
13 awareness 4yWzdW     
n.意识,觉悟,懂事,明智
参考例句:
  • There is a general awareness that smoking is harmful.人们普遍认识到吸烟有害健康。
  • Environmental awareness has increased over the years.这些年来人们的环境意识增强了。
14 diagnosis GvPxC     
n.诊断,诊断结果,调查分析,判断
参考例句:
  • His symptoms gave no obvious pointer to a possible diagnosis.他的症状无法作出明确的诊断。
  • The engineer made a complete diagnosis of the bridge's collapse.工程师对桥的倒塌做一次彻底的调查分析。
15 aspirin 4yszpM     
n.阿司匹林
参考例句:
  • The aspirin seems to quiet the headache.阿司匹林似乎使头痛减轻了。
  • She went into a chemist's and bought some aspirin.她进了一家药店,买了些阿司匹林。
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