独处不利健康——阻止独处转化为孤独
文章来源:未知 文章作者:enread 发布时间:2020-05-06 09:32 字体: [ ]  进入论坛
(单词翻译:双击或拖选)
孤独不利健康——绝对和肥胖一样糟糕,可能也和吸烟一样有害。因此,在疫情肆虐的日子里,在许多地方,人们被迫独处,如何阻止独处转化为孤独是一个紧迫的医学问题。
 
Loneliness is bad for your health—certainly as bad as being obese1, and possibly as bad as being a moderate smoker2.So, in these days of plague, when enforced solitude3 is the order of the day in many places, how to stop solitude turning into loneliness is a pressing medical question. One part of the answer is to try to understand the physiology4 of the change. And that has, for the past few years, been the objective of Steven Cole of the University of California, Los Angeles.
 
Dr Cole began his work with a study he published in 2015, in collaboration5 with John Cacioppo of the University of Chicago.
 
The pair led a team of psychologists, neuroscientists and immunologists who found that the pattern in people's blood of immune cells called myeloid cells is notably6 different in those who score as "very lonely" on loneliness tests compared with those who do not.
 
Lonely people have unusually low numbers of a type of myeloid cell that generates what are known as interferon responses, which hamper7 viral replication.
 
This makes them particularly vulnerable to viral infections. They also have an abundance of a second type of myeloid cell,one that promotes the activity of genes8 which drive inflammation— and it has been known for years that those who feel lonely experience more inflammation than those who do not.
 
These correlations9 are intriguing10, but do not explain which comes first, the loneliness or the myeloid response.
 
Dr Cole and Dr Cacioppo addressed that question by repeatedly measuring perceptions of social isolation11 in individual volunteers,while simultaneously12 tracking, from blood samples, their gene-expression patterns and other changes in their physiology.
 
They found that, initially13, volunteers' feelings of isolation coincided with an increase in their inflammation genes' activity and a concomitant increase in the circulation of immature14 immune cells, called monocytes, that are involved in inflammation— and which are also known to travel into the brain and promote anxiety.
 
They noted15, too, increased levels in the brain of signalling molecules16 associated with both inflammation and behaviours such as social withdrawal17, feelings of suspicion towards the outside world and a tendency to act more defensively by making decisions that involve few risks.
 
That, of course, promotes further feelings of loneliness. Which, in turn, trigger a further myeloid response. And so on.
 
It seems, therefore, that though loneliness starts with solitude, it can quickly take on a physiological18 life of its own.
 
Dr Cole thus worries that the enforced isolation, brought about by current circumstances, of those who are already living alone may create in many people a state of chronic19 loneliness that is difficult to escape from when things start returning to normal.
 


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1 obese uvIya     
adj.过度肥胖的,肥大的
参考例句:
  • The old man is really obese,it can't be healthy.那位老人确实过于肥胖了,不能算是健康。
  • Being obese and lazy is dangerous to health.又胖又懒危害健康。
2 smoker GiqzKx     
n.吸烟者,吸烟车厢,吸烟室
参考例句:
  • His wife dislikes him to be a smoker.他妻子不喜欢他当烟民。
  • He is a moderate smoker.他是一个有节制的烟民。
3 solitude xF9yw     
n. 孤独; 独居,荒僻之地,幽静的地方
参考例句:
  • People need a chance to reflect on spiritual matters in solitude. 人们需要独处的机会来反思精神上的事情。
  • They searched for a place where they could live in solitude. 他们寻找一个可以过隐居生活的地方。
4 physiology uAfyL     
n.生理学,生理机能
参考例句:
  • He bought a book about physiology.他买了一本生理学方面的书。
  • He was awarded the Nobel Prize for achievements in physiology.他因生理学方面的建树而被授予诺贝尔奖。
5 collaboration bW7yD     
n.合作,协作;勾结
参考例句:
  • The two companies are working in close collaboration each other.这两家公司密切合作。
  • He was shot for collaboration with the enemy.他因通敌而被枪毙了。
6 notably 1HEx9     
adv.值得注意地,显著地,尤其地,特别地
参考例句:
  • Many students were absent,notably the monitor.许多学生缺席,特别是连班长也没来。
  • A notably short,silver-haired man,he plays basketball with his staff several times a week.他个子明显较为矮小,一头银发,每周都会和他的员工一起打几次篮球。
7 hamper oyGyk     
vt.妨碍,束缚,限制;n.(有盖的)大篮子
参考例句:
  • There are some apples in a picnic hamper.在野餐用的大篮子里有许多苹果。
  • The emergence of such problems seriously hamper the development of enterprises.这些问题的出现严重阻碍了企业的发展。
8 genes 01914f8eac35d7e14afa065217edd8c0     
n.基因( gene的名词复数 )
参考例句:
  • You have good genes from your parents, so you should live a long time. 你从父母那儿获得优良的基因,所以能够活得很长。 来自《简明英汉词典》
  • Differences will help to reveal the functions of the genes. 它们间的差异将会帮助我们揭开基因多种功能。 来自英汉非文学 - 生命科学 - 生物技术的世纪
9 correlations 4a9b6fe1ddc2671881c9aa3d6cc07e8e     
相互的关系( correlation的名词复数 )
参考例句:
  • One would expect strong and positive correlations between both complexes. 人们往往以为这两个综合体之间有紧密的正相关。
  • The correlations are of unequal value. 这些对应联系的价值并不相同。
10 intriguing vqyzM1     
adj.有趣的;迷人的v.搞阴谋诡计(intrigue的现在分词);激起…的好奇心
参考例句:
  • These discoveries raise intriguing questions. 这些发现带来了非常有趣的问题。
  • It all sounds very intriguing. 这些听起来都很有趣。 来自《简明英汉词典》
11 isolation 7qMzTS     
n.隔离,孤立,分解,分离
参考例句:
  • The millionaire lived in complete isolation from the outside world.这位富翁过着与世隔绝的生活。
  • He retired and lived in relative isolation.他退休后,生活比较孤寂。
12 simultaneously 4iBz1o     
adv.同时发生地,同时进行地
参考例句:
  • The radar beam can track a number of targets almost simultaneously.雷达波几乎可以同时追着多个目标。
  • The Windows allow a computer user to execute multiple programs simultaneously.Windows允许计算机用户同时运行多个程序。
13 initially 273xZ     
adv.最初,开始
参考例句:
  • The ban was initially opposed by the US.这一禁令首先遭到美国的反对。
  • Feathers initially developed from insect scales.羽毛最初由昆虫的翅瓣演化而来。
14 immature Saaxj     
adj.未成熟的,发育未全的,未充分发展的
参考例句:
  • Tony seemed very shallow and immature.托尼看起来好像很肤浅,不夠成熟。
  • The birds were in immature plumage.这些鸟儿羽翅未全。
15 noted 5n4zXc     
adj.著名的,知名的
参考例句:
  • The local hotel is noted for its good table.当地的那家酒店以餐食精美而著称。
  • Jim is noted for arriving late for work.吉姆上班迟到出了名。
16 molecules 187c25e49d45ad10b2f266c1fa7a8d49     
分子( molecule的名词复数 )
参考例句:
  • The structure of molecules can be seen under an electron microscope. 分子的结构可在电子显微镜下观察到。
  • Inside the reactor the large molecules are cracked into smaller molecules. 在反应堆里,大分子裂变为小分子。
17 withdrawal Cfhwq     
n.取回,提款;撤退,撤军;收回,撤销
参考例句:
  • The police were forced to make a tactical withdrawal.警方被迫进行战术撤退。
  • They insisted upon a withdrawal of the statement and a public apology.他们坚持要收回那些话并公开道歉。
18 physiological aAvyK     
adj.生理学的,生理学上的
参考例句:
  • He bought a physiological book.他买了一本生理学方面的书。
  • Every individual has a physiological requirement for each nutrient.每个人对每种营养成分都有一种生理上的需要。
19 chronic BO9zl     
adj.(疾病)长期未愈的,慢性的;极坏的
参考例句:
  • Famine differs from chronic malnutrition.饥荒不同于慢性营养不良。
  • Chronic poisoning may lead to death from inanition.慢性中毒也可能由虚弱导致死亡。
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