发现:耐甲氧西林金葡菌某分支致死率非常高
文章来源:未知 文章作者:meng 发布时间:2009-11-02 06:53 字体: [ ]  进入论坛
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A strain of MRSA(耐甲氧西林金黄色葡萄球菌) that causes bloodstream infections is five times more lethal1 than other strains and has shown to have some resistance to the potent2 antibiotic3 drug vancomycin(万古霉素) used to treat MRSA, according to a Henry Ford4 Hospital study. The study found that 50 percent of the patients infected with the strain died within 30 days compared to 11 percent of patients infected with other MRSA strains.

The average 30-day mortality rate(死亡率) for MRSA bloodstream infections ranges from 10 percent to 30 percent.

Researchers say the strain USA600 contains unique characteristics that may be linked to the high mortality rate. But they say it is unclear whether other factors like the patients' older age, diseases or the spread of infection contributed to the poor outcomes collectively or with other factors. The average age of patients with the USA600 strain was 64; the average age of patients with other MRSA strains was 52.

The study is being presented at the 47th annual meeting of the Infectious Diseases Society of America Oct. 29-Nov.1 in Philadelphia.

"While many MRSA strains are associated with poor outcomes, the USA600 strain has shown to be more lethal and cause high mortality rates," says Carol Moore, PharmD., a research investigator5 in Henry Ford's Division of Infectious Diseases and lead author of the study.

"In light of(考虑到) the potential for the spread of this virulent6(有毒的,恶意的) and resistant7 strain and its associated mortality, it is essential that more effort be directed to better understanding this strain to develop measures for managing it."

MRSA, or Methicillin-resistant Staphylococcus aureus(金币), is a bacterium8 that is resistant to common antibiotics9 like penicillin10(青霉素). It can cause skin, bloodstream and surgical11 wound(外科伤口) infections and pneumonia12(肺炎). The majority of infections occur among patients in hospitals or other health care settings, though a growing number of infections are being acquired by otherwise healthy people outside those settings.

MRSA strains can be resistant to many drugs, though they are typically susceptible13 to(对……敏感) the antibiotic vancomycin. MRSA infections are often treated with vancomycin administered intravenously(静脉注射地). The USA600 strain in this study was shown to be more resistant to vancomycin.



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1 lethal D3LyB     
adj.致死的;毁灭性的
参考例句:
  • A hammer can be a lethal weapon.铁锤可以是致命的武器。
  • She took a lethal amount of poison and died.她服了致命剂量的毒药死了。
2 potent C1uzk     
adj.强有力的,有权势的;有效力的
参考例句:
  • The medicine had a potent effect on your disease.这药物对你的病疗效很大。
  • We must account of his potent influence.我们必须考虑他的强有力的影响。
3 antibiotic KNJzd     
adj.抗菌的;n.抗生素
参考例句:
  • The doctor said that I should take some antibiotic.医生说我应该服些用抗生素。
  • Antibiotic can be used against infection.抗菌素可以用来防止感染。
4 Ford KiIxx     
n.浅滩,水浅可涉处;v.涉水,涉过
参考例句:
  • They were guarding the bridge,so we forded the river.他们驻守在那座桥上,所以我们只能涉水过河。
  • If you decide to ford a stream,be extremely careful.如果已决定要涉过小溪,必须极度小心。
5 investigator zRQzo     
n.研究者,调查者,审查者
参考例句:
  • He was a special investigator for the FBI.他是联邦调查局的特别调查员。
  • The investigator was able to deduce the crime and find the criminal.调查者能够推出犯罪过程并锁定罪犯。
6 virulent 1HtyK     
adj.有毒的,有恶意的,充满敌意的
参考例句:
  • She is very virulent about her former employer.她对她过去的老板恨之入骨。
  • I stood up for her despite the virulent criticism.尽管她遭到恶毒的批评,我还是维护她。
7 resistant 7Wvxh     
adj.(to)抵抗的,有抵抗力的
参考例句:
  • Many pests are resistant to the insecticide.许多害虫对这种杀虫剂有抵抗力。
  • They imposed their government by force on the resistant population.他们以武力把自己的统治强加在持反抗态度的人民头上。
8 bacterium BN7zE     
n.(pl.)bacteria 细菌
参考例句:
  • The bacterium possibly goes in the human body by the mouth.细菌可能通过口进入人体。
  • A bacterium is identified as the cause for his duodenal ulcer.一种细菌被断定为造成他十二指肠溃疡的根源。
9 antibiotics LzgzQT     
n.(用作复数)抗生素;(用作单数)抗生物质的研究;抗生素,抗菌素( antibiotic的名词复数 )
参考例句:
  • the discovery of antibiotics in the 20th century 20世纪抗生素的发现
  • The doctor gave me a prescription for antibiotics. 医生给我开了抗生素。
10 penicillin sMXxv     
n.青霉素,盘尼西林
参考例句:
  • I should have asked him for a shot of penicillin.我应当让他给我打一针青霉素的。
  • Penicillin was an extremely significant medical discovery.青霉素是极其重要的医学发现。
11 surgical 0hXzV3     
adj.外科的,外科医生的,手术上的
参考例句:
  • He performs the surgical operations at the Red Cross Hospital.他在红十字会医院做外科手术。
  • All surgical instruments must be sterilised before use.所有的外科手术器械在使用之前,必须消毒。
12 pneumonia s2HzQ     
n.肺炎
参考例句:
  • Cage was struck with pneumonia in her youth.凯奇年轻时得过肺炎。
  • Pneumonia carried him off last week.肺炎上星期夺去了他的生命。
13 susceptible 4rrw7     
adj.过敏的,敏感的;易动感情的,易受感动的
参考例句:
  • Children are more susceptible than adults.孩子比成人易受感动。
  • We are all susceptible to advertising.我们都易受广告的影响。
TAG标签: patients MRSA lethal
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