For 80 years it has been accepted that early life began in a 'primordial¹ soup原生汤，原始汤' of organic molecules² before evolving out of the oceans millions of years later. Today the 'soup' theory has been over turned in a pioneering paper in BioEssays which claims it was the Earth's chemical energy, from hydrothermal vents深海热泉 on the ocean floor, which kick-started early life. "Textbooks have it that life arose from organic soup and that the first cells grew by fermenting使发酵，使动乱 these organics to generate energy in the form of ATP三磷酸腺苷. We provide a new perspective on why that old and familiar view won't work at all," said team leader Dr Nick lane from University College London. "We present the alternative that life arose from gases (H2, CO2, N2, and H2S) and that the energy for first life came from harnessing geochemical地球化学的 gradients渐变，梯度 created by mother Earth at a special kind of deep-sea hydrothermal vent³ – one that is riddled⁶ with tiny interconnected compartments⁷隔间，分隔 or pores气孔，毛穴."

The soup theory was proposed in 1929 when J.B.S Haldane published his influential⁸ essay on the origin of life in which he argued that UV radiation紫外线 provided the energy to convert methane⁹甲烷，沼气, ammonia氨 and water into the first organic compounds in the oceans of the early earth. However critics of the soup theory point out that there is no sustained driving force to make anything react; and without an energy source, life as we know it can't exist.

"Despite bioenergetic生物热量学 and thermodynamic热力学的 failings the 80-year-old concept of primordial soup remains¹⁰ central to mainstream¹¹ thinking on the origin of life," said senior author, William Martin, an evolutionary¹² biologist from the Insitute of Botany III in Düsseldorf. "But soup has no capacity for producing the energy vital for life."

In rejecting the soup theory the team turned to the Earth's chemistry to identify the energy source which could power the first primitive原始的，远古的 predecessors前任 of living organisms: geochemical gradients across a honeycomb of microscopic微观的 natural caverns¹⁶洞穴 at hydrothermal vents⁴. These catalytic起催化作用的 cells generated lipids脂肪，油脂, proteins and nucleotides核苷酸 giving rise to the first true cells.

The team focused on ideas pioneered by geochemist Michael J. Russell, on alkaline碱性的 deep sea vents, which produce chemical gradients very similar to those used by almost all living organisms today - a gradient of protons over a membrane¹⁷. Early organisms likely exploited these gradients through a process called chemiosmosis, in which the proton gradient is used to drive synthesis of the universal energy currency, ATP, or simpler equivalents. Later on cells evolved to generate their own proton gradient by way of electron transfer from a donor¹⁸ to an acceptor. The team argue that the first donor was hydrogen and the first acceptor was CO2.

"Modern living cells have inherited the same size of proton gradient, and, crucially, the same orientation¹⁹ – positive outside and negative inside – as the inorganic²⁰ vesicles from which they arose" said co-author John Allen, a biochemist at Queen Mary, University of London.

"Thermodynamic constraints限制，约束 mean that chemiosmosis is strictly²² necessary for carbon and energy metabolism能量代谢 in all organisms that grow from simple chemical ingredients [autotrophy] today, and presumably the first free-living cells," said Lane. "Here we consider how the earliest cells might have harnessed a geochemically created force and then learned to make their own."

This was a vital transition, as chemiosmosis is the only mechanism²⁴ by which organisms could escape from the vents. "The reason that all organisms are chemiosmotic today is simply that they inherited it from the very time and place that the first cells evolved – and they could not have evolved without it," said Martin.

"Far from being too complex to have powered early life, it is nearly impossible to see how life could have begun without chemiosmosis化学渗透", concluded Lane. "It is time to cast off the shackles手铐，脚镣 of fermentation发酵 in some primordial soup as 'life without oxygen' – an idea that dates back to a time before anybody in biology had any understanding of how ATP is made."