In an important breakthrough, scientists at McMaster University have discovered how to make human blood from adult human skin. The discovery, published in the prestigious¹（有名望的） science journal Nature today, could mean that in the foreseeable（可预知的） future people needing blood for surgery, cancer treatment or treatment of other blood conditions like anemia²（贫血） will be able to have blood created from a patch of their own skin to provide transfusions³（输血，注入） . Clinical trials could begin as soon as 2012.

Mick Bhatia, scientific director of McMaster's Stem Cell and Cancer Research Institute in the Michael G. DeGroote School of Medicine, and his team of researchers have also shown that the conversion⁴ is direct. Making blood from skin does not require the middle step of changing a skin stem cell into a pluripotent（多能的） stem cell that could make many other types of human cells, then turning it into a blood stem cell.

"We have shown this works using human skin. We know how it works and believe we can even improve on the process," said Bhatia. "We'll now go on to work on developing other types of human cell types from skin, as we already have encouraging evidence."

The discovery was replicated⁵（复制，折叠） several times over two years using human skin from both young and old people to prove it works for any age of person.