腹部脂肪过多加重女性骨质疏松危险
文章来源:未知 文章作者:meng 发布时间:2010-12-01 03:24 字体: [ ]  进入论坛
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For years, it was believed that obese1 women were at lower risk for developing osteoporosis(骨质疏松症) , and that excess body fat actually protected against bone loss. However, a study presented today at the annual meeting of the Radiological Society of North America (RSNA) found that having too much internal abdominal2(腹部的) fat may, in fact, have a damaging effect on bone health. "We know that obesity3 is a major public health problem," said the study's lead author, Miriam A. Bredella, M.D., a radiologist at Massachusetts General Hospital and assistant professor of radiology at Harvard Medical School in Boston. "Now we know that abdominal obesity needs to be included as a risk factor for osteoporosis and bone loss."

According to the Centers for Disease Control and Prevention (CDC), approximately 72 million American adults are considered obese. The CDC defines obesity as having a body mass index (BMI) of 30 or more. Obesity is associated with many health problems including cardiovascular diseases, diabetes4, high cholesterol5, asthma6, sleep apnea(睡眠呼吸暂停) and joint7 diseases. Yet despite all the health issues, it was commonly accepted that women with increased body weight were at lower risk for bone loss.

But not all body fat is the same. Subcutaneous fat(皮下脂肪) lies just below the skin, and visceral(内脏的) or intra-abdominal fat is located deep under the muscle tissue in the abdominal cavity. Genetics, diet and exercise are all contributors to the level of visceral fat that is stored in the body. Excess visceral fat is considered particularly dangerous, because in previous studies it has been associated with increased risk for heart disease.

Dr. Bredella and colleagues set out to evaluate the abdominal subcutaneous, visceral and total fat, as well as bone marrow8 fat and bone mineral density9, in 50 premenopausal women with a mean BMI of 30. Each woman underwent an MR spectroscopy exam to evaluate the bone marrow fat of the L4, the fourth vertebra in the lumbar section of the spine10. Then, the bone mineral density of the L4 was assessed using quantitative11 computed12 tomography (QCT), which measures bone mass and is used to assess bone loss.

The imaging revealed that women with more visceral fat had increased bone marrow fat and decreased bone mineral density. However, there was no significant correlation13 between either subcutaneous fat or total fat and bone marrow fat or bone mineral density. "Our results showed that having a lot of belly14 fat is more detrimental15 to(对……不利) bone health than having more superficial fat or fat around the hips," Dr. Bredella said.

According to the National Women's Health Information Center, 10 million Americans have osteoporosis and 18 million more have low bone mass, placing them at risk for the disease.

"It is important for the public to be aware that excess belly fat is a risk factor for bone loss, as well as heart disease and diabetes," Dr. Bredella said.

While bone loss is more common in women, the research team is currently conducting a study to determine whether belly fat is also a risk factor for bone loss in men.



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1 obese uvIya     
adj.过度肥胖的,肥大的
参考例句:
  • The old man is really obese,it can't be healthy.那位老人确实过于肥胖了,不能算是健康。
  • Being obese and lazy is dangerous to health.又胖又懒危害健康。
2 abdominal VIUya     
adj.腹(部)的,下腹的;n.腹肌
参考例句:
  • The abdominal aorta is normally smaller than the thoracic aorta.腹主动脉一般比胸主动脉小。
  • Abdominal tissues sometimes adhere after an operation.手术之后腹部有时会出现粘连。
3 obesity Dv1ya     
n.肥胖,肥大
参考例句:
  • One effect of overeating may be obesity.吃得过多能导致肥胖。
  • Sugar and fat can more easily lead to obesity than some other foods.糖和脂肪比其他食物更容易导致肥胖。
4 diabetes uPnzu     
n.糖尿病
参考例句:
  • In case of diabetes, physicians advise against the use of sugar.对于糖尿病患者,医生告诫他们不要吃糖。
  • Diabetes is caused by a fault in the insulin production of the body.糖尿病是由体內胰岛素分泌失调引起的。
5 cholesterol qrzzV     
n.(U)胆固醇
参考例句:
  • There is cholesterol in the cell of body.人体细胞里有胆固醇。
  • They are determining the serum-protein and cholesterol levels.他们正在测定血清蛋白和胆固醇的浓度。
6 asthma WvezQ     
n.气喘病,哮喘病
参考例句:
  • I think he's having an asthma attack.我想他现在是哮喘病发作了。
  • Its presence in allergic asthma is well known.它在过敏性气喘中的存在是大家很熟悉的。
7 joint m3lx4     
adj.联合的,共同的;n.关节,接合处;v.连接,贴合
参考例句:
  • I had a bad fall,which put my shoulder out of joint.我重重地摔了一跤,肩膀脫臼了。
  • We wrote a letter in joint names.我们联名写了封信。
8 marrow M2myE     
n.骨髓;精华;活力
参考例句:
  • It was so cold that he felt frozen to the marrow. 天气太冷了,他感到寒冷刺骨。
  • He was tired to the marrow of his bones.他真是累得筋疲力尽了。
9 density rOdzZ     
n.密集,密度,浓度
参考例句:
  • The population density of that country is 685 per square mile.那个国家的人口密度为每平方英里685人。
  • The region has a very high population density.该地区的人口密度很高。
10 spine lFQzT     
n.脊柱,脊椎;(动植物的)刺;书脊
参考例句:
  • He broke his spine in a fall from a horse.他从马上跌下摔断了脊梁骨。
  • His spine developed a slight curve.他的脊柱有点弯曲。
11 quantitative TCpyg     
adj.数量的,定量的
参考例句:
  • He said it was only a quantitative difference.他说这仅仅是数量上的差别。
  • We need to do some quantitative analysis of the drugs.我们对药物要进行定量分析。
12 computed 5a317d3dd3f7a2f675975a6d0c11c629     
adj.[医]计算的,使用计算机的v.计算,估算( compute的过去式和过去分词 )
参考例句:
  • He computed that the project would take seven years to complete. 他估计这项计划要花七年才能完成。 来自《简明英汉词典》
  • Resolving kernels and standard errors can also be computed for each block. 还可以计算每个块体的分辨核和标准误差。 来自辞典例句
13 correlation Rogzg     
n.相互关系,相关,关连
参考例句:
  • The second group of measurements had a high correlation with the first.第二组测量数据与第一组高度相关。
  • A high correlation exists in America between education and economic position.教育和经济地位在美国有极密切的关系。
14 belly QyKzLi     
n.肚子,腹部;(像肚子一样)鼓起的部分,膛
参考例句:
  • The boss has a large belly.老板大腹便便。
  • His eyes are bigger than his belly.他眼馋肚饱。
15 detrimental 1l2zx     
adj.损害的,造成伤害的
参考例句:
  • We know that heat treatment is detrimental to milk.我们知道加热对牛奶是不利的。
  • He wouldn't accept that smoking was detrimental to health.他不相信吸烟有害健康。
TAG标签: body bone women osteoporosis
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