钙摄入过多易诱发前列腺癌
文章来源:未知 文章作者:enread 发布时间:2011-09-19 05:42 字体: [ ]  进入论坛
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A study by epidemiologists at Wake Forest Baptist Medical Center and colleagues suggests that a high intake1 of calcium2(钙) causes prostate cancer among African-American men who are genetically4 good absorbers of the mineral. "High dietary intake of calcium has long been linked to prostate cancer but the explanation for this observation has been elusive," said Gary G. Schwartz, Ph.D., associate professor of cancer biology, urology, and public health sciences at Wake Forest Baptist and co-author on the study.
Schwartz and colleagues from the Keck School of Medicine at the University of Southern California (USC) and the Cancer Prevention Institute of California studied 783 African-American men living in the San Francisco and Los Angeles areas, 533 of whom were diagnosed with prostate cancer. They studied the effects of genotype, calcium intake and diet-gene interactions.
The study is one of the few to explore genes5 related to calcium absorption or to examine diet in a large African-American population. Although prostate cancer is 36 percent more common among African-Americans than in non-Hispanic whites, data on the diet-cancer link primarily comes from Caucasian populations. The team targeted a genetic3 allele(等位基因) that is more common in populations of African origin than in other populations and which is associated with regulating the absorption of calcium.
In the United States, more than 240,000 men are diagnosed annually6 with prostate cancer and about 33,720 die from the disease, according to the National Cancer Institute. Only lung cancer kills more American men. According to the Prostate Cancer Foundation, there are no proven strategies for preventing the disease, but changes in diet and lifestyle have shown to reduce the risk of disease progression.
The study, which is now available in the online issue of the Journal of Bone and Mineral Research, found that men who reported the highest intake of calcium were two times more likely to have localized and advanced prostate cancer than those who reported the lowest. Men with a genotype associated with poor calcium absorption were 59 percent less likely to have been diagnosed with advanced prostate cancer than men who genetically were the best absorbers of calcium. And, among men with calcium intake below the median, genetically poor absorbers had a 50 percent decreased risk of having advanced prostate cancer than the best absorbers. The final paper is scheduled to appear in the January 2012 print issue.


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1 intake 44cyQ     
n.吸入,纳入;进气口,入口
参考例句:
  • Reduce your salt intake.减少盐的摄入量。
  • There was a horrified intake of breath from every child.所有的孩子都害怕地倒抽了一口凉气。
2 calcium sNdzY     
n.钙(化学符号Ca)
参考例句:
  • We need calcium to make bones.我们需要钙来壮骨。
  • Calcium is found most abundantly in milk.奶含钙最丰富。
3 genetic PgIxp     
adj.遗传的,遗传学的
参考例句:
  • It's very difficult to treat genetic diseases.遗传性疾病治疗起来很困难。
  • Each daughter cell can receive a full complement of the genetic information.每个子细胞可以收到遗传信息的一个完全补偿物。
4 genetically Lgixo     
adv.遗传上
参考例句:
  • All the bees in the colony are genetically related. 同一群体的蜜蜂都有亲缘关系。
  • Genetically modified foods have already arrived on American dinner tables. 经基因改造加工过的食物已端上了美国人的餐桌。 来自英汉非文学 - 生命科学 - 基因与食物
5 genes 01914f8eac35d7e14afa065217edd8c0     
n.基因( gene的名词复数 )
参考例句:
  • You have good genes from your parents, so you should live a long time. 你从父母那儿获得优良的基因,所以能够活得很长。 来自《简明英汉词典》
  • Differences will help to reveal the functions of the genes. 它们间的差异将会帮助我们揭开基因多种功能。 来自英汉非文学 - 生命科学 - 生物技术的世纪
6 annually VzYzNO     
adv.一年一次,每年
参考例句:
  • Many migratory birds visit this lake annually.许多候鸟每年到这个湖上作短期逗留。
  • They celebrate their wedding anniversary annually.他们每年庆祝一番结婚纪念日。
TAG标签: prostate cancer calcium
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