基因突变使马匹易感染西尼罗河病毒
文章来源:未知 文章作者:meng 发布时间:2010-06-03 02:25 字体: [ ]  进入论坛
(单词翻译:双击或拖选)

The same mutated gene1 that makes humans more susceptible2 to the potentially fatal West Nile virus is also responsible for the virus affecting horses, according to scientists at the University of Adelaide, Australia. A naturally occurring mutation3(突变,变化) of the OAS1 gene has now been confirmed as increasing the vulnerability(弱点,易损性) of horses to the West Nile virus, thanks to a study led by Professor David Adelson (University of Adelaide) and conducted by PhD student Jonathan Rios (Texas A&M University).

The results of the study were published last month in the online peer-reviewed science journal PLoS One.

West Nile virus causes inflammation(发炎,炎症) of the brain and spinal4 cord(脊髓) , resulting in paralysis5(麻痹,无力) and death in humans, horses, birds and other species.

"Horses have been seriously affected6 by the West Nile virus, especially in North America where vaccinations7, treatments and the loss of horses have cost countless8 millions of dollars to horse owners, industry and the community," says Professor Adelson, who is Professor of Bioinformatics(生物信息学) and Computational Genetics at the University of Adelaide's School of Molecular10 & Biomedical Science.

"The OAS gene cluster in horses most closely resembles that of humans. Because previous research had already identified mutations of OAS1 as playing a key role in the vulnerability of mice and humans to the West Nile virus, we felt it was worth investigating this potential link in horses.

"These genetic9 mechanisms11 seem to be playing a similar role in humans and horses in terms of(依据,按照) allowing the West Nile virus to take its hold on the body.

"We believe this discovery will be of great interest to horse owners and those involved in controlling the spread of the virus. Knowing that a mutated OAS1 gene is playing a key role in this problem, valuable horses could be screened to check for the presence of the mutation and therefore susceptibility to the virus," Professor Adelson says.

According to the Centers for Disease Control and Infection, in 2009 there were 720 reported human cases of West Nile virus across the United States, including more than 30 deaths.

The virus has been found in Africa, Europe, the Middle East, Asia and Oceania as well in North America. Australia remains12 free of the virus at this stage.



点击收听单词发音收听单词发音  

1 gene WgKxx     
n.遗传因子,基因
参考例句:
  • A single gene may have many effects.单一基因可能具有很多种效应。
  • The targeting of gene therapy has been paid close attention.其中基因治疗的靶向性是值得密切关注的问题之一。
2 susceptible 4rrw7     
adj.过敏的,敏感的;易动感情的,易受感动的
参考例句:
  • Children are more susceptible than adults.孩子比成人易受感动。
  • We are all susceptible to advertising.我们都易受广告的影响。
3 mutation t1PyM     
n.变化,变异,转变
参考例句:
  • People who have this mutation need less sleep than others.有这种突变的人需要的睡眠比其他人少。
  • So far the discussion has centered entirely around mutation in the strict sense.到目前为止,严格来讲,讨论完全集中于围绕突变问题上。
4 spinal KFczS     
adj.针的,尖刺的,尖刺状突起的;adj.脊骨的,脊髓的
参考例句:
  • After three days in Japan,the spinal column becomes extraordinarily flexible.在日本三天,就已经使脊椎骨变得富有弹性了。
  • Your spinal column is made up of 24 movable vertebrae.你的脊柱由24个活动的脊椎骨构成。
5 paralysis pKMxY     
n.麻痹(症);瘫痪(症)
参考例句:
  • The paralysis affects his right leg and he can only walk with difficulty.他右腿瘫痪步履维艰。
  • The paralysis affects his right leg and he can only walk with difficulty.他右腿瘫痪步履维艰。
6 affected TzUzg0     
adj.不自然的,假装的
参考例句:
  • She showed an affected interest in our subject.她假装对我们的课题感到兴趣。
  • His manners are affected.他的态度不自然。
7 vaccinations ed61d339e2970fa63aee4b5ce757cc44     
n.种痘,接种( vaccination的名词复数 );牛痘疤
参考例句:
  • Vaccinations ensure one against diseases. 接种疫苗可以预防疾病。 来自《简明英汉词典》
  • I read some publicity about vaccinations while waiting my turn at the doctor's. 在医生那儿候诊时,我读了一些关于接种疫苗的宣传。 来自《简明英汉词典》
8 countless 7vqz9L     
adj.无数的,多得不计其数的
参考例句:
  • In the war countless innocent people lost their lives.在这场战争中无数无辜的人丧失了性命。
  • I've told you countless times.我已经告诉你无数遍了。
9 genetic PgIxp     
adj.遗传的,遗传学的
参考例句:
  • It's very difficult to treat genetic diseases.遗传性疾病治疗起来很困难。
  • Each daughter cell can receive a full complement of the genetic information.每个子细胞可以收到遗传信息的一个完全补偿物。
10 molecular mE9xh     
adj.分子的;克分子的
参考例句:
  • The research will provide direct insight into molecular mechanisms.这项研究将使人能够直接地了解分子的机理。
  • For the pressure to become zero, molecular bombardment must cease.当压强趋近于零时,分子的碰撞就停止了。
11 mechanisms d0db71d70348ef1c49f05f59097917b8     
n.机械( mechanism的名词复数 );机械装置;[生物学] 机制;机械作用
参考例句:
  • The research will provide direct insight into molecular mechanisms. 这项研究将使人能够直接地了解分子的机理。 来自《简明英汉词典》
  • He explained how the two mechanisms worked. 他解释这两台机械装置是如何工作的。 来自《简明英汉词典》
12 remains 1kMzTy     
n.剩余物,残留物;遗体,遗迹
参考例句:
  • He ate the remains of food hungrily.他狼吞虎咽地吃剩余的食物。
  • The remains of the meal were fed to the dog.残羹剩饭喂狗了。
TAG标签: virus science gene horses
发表评论
请自觉遵守互联网相关的政策法规,严禁发布色情、暴力、反动的言论。
评价:
表情:
验证码:点击我更换图片