改变蚊子的遗传基因可能控制寨卡病毒传播
文章来源:未知 文章作者:enread 发布时间:2016-03-15 06:09 字体: [ ]  进入论坛
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Genetic2 cues from male Aedes aegypti mosquitoes passed on during sex affect which genes3 are turned on or off in a females' reproductive tract4 post-mating, including genes related to blood feeding, egg development and immune defense5, according to new Cornell research. The researchers believe such processes provide information that could be exploited to fight mosquito-borne diseases, such as dengue fever, chikungunya and Zika virus.
 
"We have two main goals," said Laura Harrington, professor of entomology and a co-author of a paper published Feb. 22 in the Public Library of Science for Neglected Tropical Diseases. "The first is to understand the basic biology of the mosquito mating system, and the second is to try to understand it in a way that we can develop novel strategies for controlling the mosquito. We are focusing on reproduction because we see it as the Achilles heel of the mosquito."
 
The research draws from previous findings by molecular6 biology and genetics professor and study co-author Mariana Wolfner on how Drosophila females' gene1 expression, behavior and physiology7 are changed by mating. That work revealed that after mating, seminal8 fluid proteins passed from males to females led to changes in gene expression in females and led females to increase egg production, reduce feeding and decrease their likelihood to mate again.
 
In this study, the researchers used sequencing to identify changes in RNA populations in the lower reproductive tract of female mosquitoes in response to mating. RNA is the chemical messenger by which the information in genes is translated into protein.
 
In the study, the researchers measured changes in the levels of specific RNAs in the female after mating to determine which proteins became more and less abundant. The findings are a step towards understanding what molecules9 are necessary to prepare a female for producing progeny10.


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1 gene WgKxx     
n.遗传因子,基因
参考例句:
  • A single gene may have many effects.单一基因可能具有很多种效应。
  • The targeting of gene therapy has been paid close attention.其中基因治疗的靶向性是值得密切关注的问题之一。
2 genetic PgIxp     
adj.遗传的,遗传学的
参考例句:
  • It's very difficult to treat genetic diseases.遗传性疾病治疗起来很困难。
  • Each daughter cell can receive a full complement of the genetic information.每个子细胞可以收到遗传信息的一个完全补偿物。
3 genes 01914f8eac35d7e14afa065217edd8c0     
n.基因( gene的名词复数 )
参考例句:
  • You have good genes from your parents, so you should live a long time. 你从父母那儿获得优良的基因,所以能够活得很长。 来自《简明英汉词典》
  • Differences will help to reveal the functions of the genes. 它们间的差异将会帮助我们揭开基因多种功能。 来自英汉非文学 - 生命科学 - 生物技术的世纪
4 tract iJxz4     
n.传单,小册子,大片(土地或森林)
参考例句:
  • He owns a large tract of forest.他拥有一大片森林。
  • He wrote a tract on this subject.他曾对此写了一篇短文。
5 defense AxbxB     
n.防御,保卫;[pl.]防务工事;辩护,答辩
参考例句:
  • The accused has the right to defense.被告人有权获得辩护。
  • The war has impacted the area with military and defense workers.战争使那个地区挤满了军队和防御工程人员。
6 molecular mE9xh     
adj.分子的;克分子的
参考例句:
  • The research will provide direct insight into molecular mechanisms.这项研究将使人能够直接地了解分子的机理。
  • For the pressure to become zero, molecular bombardment must cease.当压强趋近于零时,分子的碰撞就停止了。
7 physiology uAfyL     
n.生理学,生理机能
参考例句:
  • He bought a book about physiology.他买了一本生理学方面的书。
  • He was awarded the Nobel Prize for achievements in physiology.他因生理学方面的建树而被授予诺贝尔奖。
8 seminal Qzrwo     
adj.影响深远的;种子的
参考例句:
  • The reforms have been a seminal event in the history of the NHS.这些改革已成为英国国民保健制度史上影响深远的一件大事。
  • The emperor's importance as a seminal figure of history won't be diminished.做为一个开创性历史人物的重要性是不会减弱的。
9 molecules 187c25e49d45ad10b2f266c1fa7a8d49     
分子( molecule的名词复数 )
参考例句:
  • The structure of molecules can be seen under an electron microscope. 分子的结构可在电子显微镜下观察到。
  • Inside the reactor the large molecules are cracked into smaller molecules. 在反应堆里,大分子裂变为小分子。
10 progeny ZB5yF     
n.后代,子孙;结果
参考例句:
  • His numerous progeny are scattered all over the country.他为数众多的后代散布在全国各地。
  • He was surrounded by his numerous progeny.众多的子孙簇拥着他。
TAG标签: virus genes mosquito
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