中国发现大规模生产青蒿素新方法_科学技术

中国发现大规模生产青蒿素新方法

文章来源：未知文章作者：enread 发布时间：2019-05-13 09:20 字体： [大中小]　进入论坛

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Chinese researchers have developed a new technology to produce artemisinin.

中国科研人员发现一种生产青蒿素的新方法。

Sweet wormwood was used in ancient Chinese therapy to treat various illnesses, including fevers typical of malaria¹. Nearly five decades ago, Chinese scientists identified its active ingredient, artemisinin.

In 2005, the World Health Organization recommended Artemisinin-based Combination Therapies (ACTs) as the most effective malaria treatment available. Global demand for artemisinin then increased, but the quality and supply have not been stable.

According to researchers from the Institute of Process Engineering (IPE), Chinese Academy of Sciences, due to its complex structure, artemisinin is currently difficult and not economically feasible to chemically synthesize.

The traditional industrial method to produce artemisinin is to treat sweet wormwood leaves with organic solvents³ like petroleum⁴ ether.

The extraction process is long, energy consumption is high and productivity is low.

In the study, the IPE researchers proposed to enhance the contact between the solvent² and the leaves by reflux to speed up the artemisinin extraction.

The extraction time was reduced from seven hours to four and a half hours.

After treating sweet wormwood leaves with solvents, they optimized⁵ the evaporation⁶ process with a thin film evaporator, an apparatus⁷ that provides a continuous evaporation process, especially for heat-sensitive products, to retrieve⁸ the solvents.

Compared to the traditional process, the time it takes to produce the artemisinin concentrate is reduced by 87.5 percent.

Meanwhile, the purity of the final product is increased to more than 99 percent, and energy consumption is also reduced.

The new technology makes the recovery of the solvents reach 99.9 percent, energy consumption per ton of artemisinin drop by 43 percent and the product purity is higher than 99 percent, said Wang Hui from the IPE.

"This technology solves the main shortcomings in the traditional artemisinin production process and could also provide ideas for other natural products production," said Zhang Suojiang, the director of IPE.

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收听单词发音

1 malaria
n.疟疾
参考例句：
He had frequent attacks of malaria.他常患疟疾。 Malaria is a kind of serious malady.疟疾是一种严重的疾病。

2 solvent
n.溶剂；adj.有偿付能力的
参考例句：
Gasoline is a solvent liquid which removes grease spots.汽油是一种能去掉油污的有溶解力的液体。 A bankrupt company is not solvent.一个破产的公司是没有偿还债务的能力的。

3 solvents
溶解的，溶剂
参考例句：
It is resistant to borohydride reduction in alcoholic solvents. 在醇溶剂中，它不能被硼氢化物还原。 Strains require special treatments for removal such as spotting with organic solvents. 要清除这些着色物质，需要特殊处理，例如：滴加有机溶剂。

4 petroleum
n.原油，石油
参考例句：
The Government of Iran advanced the price of petroleum last week.上星期伊朗政府提高了石油价格。 The purpose of oil refinery is to refine crude petroleum.炼油厂的主要工作是提炼原油。

5 optimized
adj.最佳化的，（使）最优化的v.使最优化，使尽可能有效( optimize的过去式和过去分词 )
参考例句：
We are often asked whether consumer Web sites should be optimized for beginners or intermediates. 我们常常被问到这样的问题：消费类网站究竟应该为新手而优化，还是应该为中间用户而优化？来自About Face 3交互设计精髓 GOOGLE Advertising optimized sequence, greatly increasing the advertising effect. 优化了GOOGLE广告位排列顺序，大大增加了广告效果。来自互联网

6 evaporation
n.蒸发，消失
参考例句：
Be careful not to lose too much liquid by evaporation.小心不要因蒸发失去太多水分。 Our bodies can sweat,thereby losing heat by evaporation.我们的身体能出汗，由此可以蒸发散热。

7 apparatus
n.装置，器械；器具，设备
参考例句：
The school's audio apparatus includes films and records.学校的视听设备包括放映机和录音机。 They had a very refined apparatus.他们有一套非常精良的设备。

8 retrieve
vt.重新得到，收回；挽回，补救；检索
参考例句：
He was determined to retrieve his honor.他决心恢复名誉。 The men were trying to retrieve weapons left when the army abandoned the island.士兵们正试图找回军队从该岛撤退时留下的武器。

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