Infection-allergy link questioned 专家质疑传染病与过敏间的联
文章来源:未知 文章作者:meng 发布时间:2009-09-09 06:46 字体: [ ]  进入论坛

The notion of exposing young children to infections in a bid to protect them from later allergies1 is wrong, latest research suggests.


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Catching infections early on in life may do no good

The decades-old "hygiene3(卫生) hypothesis" holds that early exposure to microbes(微生物) somehow challenges the immune system and strengthens it against allergies.

Studies have shown children exposed to bugs4 by older siblings5 or attending nursery cut their future allergy6 risk.

But new work published by the American Thoracic Society casts doubt on this.

No benefit

The study by Dutch investigators7 at the Erasmus University found although children in day care got more colds and other infections, they were just as likely as other children to go on to develop asthma8(哮喘) or another allergy(敏感,反感) by the age of eight.

The children who went to nursery and who had older siblings had more than quadruple(四倍) the risk of frequent chest infections and double the risk of wheezing9(喘息) in early life, with no obvious pay off in terms of later protection from allergy.

The infections may, therefore, do more harm than good, contrary to common belief, the authors told the American Journal of Respiratory and Critical Care Medicine.

Lead author of the study on 4,000 children, Dr Johan de Jongste, said: "Early day care should not be promoted for reasons of preventing asthma and allergy.

"Early day care merely seems to shift the burden of respiratory(呼吸的) morbidity10(病态) to an earlier age where it is more troublesome than at a later age."

Other experts have questioned if we need exposure to dirt and germs to build a balanced and healthy immune system.

Too clean?

Experience shows children who grow up on farms are less likely to develop allergies like hay fever and asthma.

And there is the belief that too much cleanliness is not a good thing, and our excessive use of disinfectant products is partly to blame for the recent allergy boom.

But Professor Sally Bloomfield from the International Scientific Forum11 on Home Hygiene disagrees. She said: "There is no evidence at all for this. However much we clean our homes we are still constantly exposed to microbes."

A spokeswoman from Allergy UK said: "There is some truth in the hygiene hypothesis. Certainly, little Johnny playing in the mud and growing up on a farm may be more healthy than other children. And we are probably mollycoddling12(女性化的男人,娇生惯养的男人) our children a little too much.

"But allergies run in families. In susceptible13(易受影响的) individuals, there is something in their environment that triggers the allergy. For asthma, that could be a dusty home."

Dr Elaine Vickers of Asthma UK said: "The hygiene hypothesis is a hot topic of debate in the research community.

"Whatever the truth, the best advice we can currently give to parents is not to smoke around their children and make sure they have a balanced diet and get plenty of exercise."


1 allergies 2c527dd68e63f119442f4352f2a0b950     
n.[医]过敏症;[口]厌恶,反感;(对食物、花粉、虫咬等的)过敏症( allergy的名词复数 );变态反应,变应性
  • Food allergies can result in an enormous variety of different symptoms. 食物过敏会引发很多不同的症状。 来自辞典例句
  • Let us, however, examine one of the most common allergies; hayfever. 现在让我们来看看最常见的变态反应的一种--枯草热。 来自辞典例句
2 catching cwVztY     
  • There are those who think eczema is catching.有人就是认为湿疹会传染。
  • Enthusiasm is very catching.热情非常富有感染力。
3 hygiene Kchzr     
n.健康法,卫生学 (a.hygienic)
  • Their course of study includes elementary hygiene and medical theory.他们的课程包括基础卫生学和医疗知识。
  • He's going to give us a lecture on public hygiene.他要给我们作关于公共卫生方面的报告。
4 bugs e3255bae220613022d67e26d2e4fa689     
adj.疯狂的,发疯的n.窃听器( bug的名词复数 );病菌;虫子;[计算机](制作软件程序所产生的意料不到的)错误
  • All programs have bugs and need endless refinement. 所有的程序都有漏洞,都需要不断改进。 来自《简明英汉词典》
  • The sacks of rice were swarming with bugs. 一袋袋的米里长满了虫子。 来自《简明英汉词典》
5 siblings 709961e45d6808c7c9131573b3a8874b     
n.兄弟,姐妹( sibling的名词复数 )
  • A triplet sleeps amongst its two siblings. 一个三胞胎睡在其两个同胞之间。 来自《简明英汉词典》
  • She has no way of tracking the donor or her half-siblings down. 她没办法找到那个捐精者或她的兄弟姐妹。 来自时文部分
6 allergy 8Vpza     
  • He developed an allergy to pollen.他对花粉过敏。
  • The patient had an allergy to penicillin.该患者对青霉素过敏。
7 investigators e970f9140785518a87fc81641b7c89f7     
n.调查者,审查者( investigator的名词复数 )
  • This memo could be the smoking gun that investigators have been looking for. 这份备忘录可能是调查人员一直在寻找的证据。
  • The team consisted of six investigators and two secretaries. 这个团队由六个调查人员和两个秘书组成。 来自《简明英汉词典》
8 asthma WvezQ     
  • I think he's having an asthma attack.我想他现在是哮喘病发作了。
  • Its presence in allergic asthma is well known.它在过敏性气喘中的存在是大家很熟悉的。
9 wheezing 725d713049073d5b2a804fc762d3b774     
v.喘息,发出呼哧呼哧的喘息声( wheeze的现在分词 );哮鸣
  • He was coughing and wheezing all night. 他整夜又咳嗽又喘。
  • A barrel-organ was wheezing out an old tune. 一架手摇风琴正在呼哧呼哧地奏着一首古老的曲子。 来自《现代汉英综合大词典》
10 morbidity OEBxK     
  • MC's also significantly reduce the morbidity and mortality induced by honeybee venom. 肥大细胞同样也能显著降低蜜蜂毒液诱发疾病的发病率和死亡率。 来自互联网
  • The result shows that incidence of myopia morbidity is 44.84%. 结果表明:近视眼的发病率为44.84%。 来自互联网
11 forum cilx0     
  • They're holding a forum on new ways of teaching history.他们正在举行历史教学讨论会。
  • The organisation would provide a forum where problems could be discussed.这个组织将提供一个可以讨论问题的平台。
12 mollycoddling 5f70137a6d6a58a60af256c86d1b9b09     
v.娇养,宠坏( mollycoddle的现在分词 )
  • Stop mollycoddling me;I'm a grown person. 别再过分照料我了;我是一个大人了。 来自互联网
13 susceptible 4rrw7     
  • Children are more susceptible than adults.孩子比成人易受感动。
  • We are all susceptible to advertising.我们都易受广告的影响。
TAG标签: children allergy infection